Cameasha Turner led all scorers with 19 points, and added seven rebounds, but it wasn't enough as UTSA dominated the boards, and picked apart UTEP on the offensive end in a 72-59 win.
Both Tesha Smith and Mannasha Bell recorded double-doubles for UTSA, Smith finished with 17 points and 14 rebounds, while Bell put up 15 points and 11 rebounds.
UTSA used 18 offensive rebounds to win the battle of the boards by a 32-20 advantage.
The Miners would get off to a hot start in the first two and a half minutes of the game, jumping out to an early 9-2 lead after Stacie Telles drilled a three pointer at the 17:40 mark.
UTEP held UTSA to only two field goals in the first five minutes of the game, but the Runners would go on a quick 10-1 run capped off by a bucket from Crystal Chidmore to put UTSA ahead 14-11 with 13:22 left until halftime.
Answering with a 9-3 swing, UTEP took a 20-17 lead after Daeshianna McCants laid one in as the game's first ten minutes came and went.
UTSA would end up out scoring UTEP 15-5 in the final ten minutes of the first half to take a 32-25 lead into the halftime break.
Scoring 18 of their first half points in the paint, UTSA continued to pound the paint in the second half as Bell hit a jumper from inside the paint to stretch the Runner lead to 43-29 at the 13:52 mark of the second half.
But then Lulu McKinney and Stacie Telles dialed up back-to-back threes to cut the lead to 43-35 just seconds later.
UTEP struggled from the floor shooting 31.7 percent from the field, but Stacie Telles who finished with 14 points hit another three pointer to bring UTEP within single digits trailing 50-41 with 8:13 left to play.
Nine points was as close as UTEP would get the rest of the way, UTSA shot 46.3 percent for the game and the Roadrunners lead by as much as 14 in the final five minutes to close out the win.
Spakle Taylor finished with nine points, and seven rebounds, McKinney added eight points but was 2/9 from the field.
UTEP's record now stands at 10-13 overall, and 5-9 in C-USA play, ending their three game with road trip with a two game home stand coming up next Thursday, and Saturday.